A Taliban suicide bomber struck inside one of Pakistan's major cities for the second time this week. Just four days after a suicide bomber killed five UN employees at World Food Program offices in Islamabad, another bomber detonated a car packed with explosives at a bazaar in Peshawar, the capital of the Northwest Frontier Province.

Forty-nine people have been reported killed and more than 100 have been wounded, some critically, after the suicide bomber detonated more than 100 kilograms of explosives packed in a car in the Khyber Bazaar, one of the busiest markets in the provincial capital. More than 50 people have been reported as critically wounded.

The bomb was built to inflict "maximum casualties," according to police.

"The device was planted in the door panels of the vehicle and included machine gun ammunition, designed to cause maximum casualties," Dawn reported.

Today's attack is the second since Hakeemullah Mehsud, the leader of the Movement of the Taliban in Pakistan, and his regional commanders held a press conference in South Waziristan and vowed to restart a suicide campaign in Pakistan. Hakeemullah said the attacks would continue until the military halted operations in the tribal areas.

The Taliban last struck in Peshawar on Sept. 26, when a suicide bomber detonated an explosive-laden car outside of a bank and a military housing complex. Twenty people were killed and more than 100 were wounded in the suicide attack.

That same day, a suicide bomber rammed his truck into a police station in Bannu, killing 10 people and wounding dozens more.